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Theme 4: Health effects of noise and air pollution including nanoparticles

Theme 4: Introduction

Overall aim of this theme:  To advance the scientific evidence base to support public health protection with respect to ambient air pollution (including nanoparticles) and transport related noise.

Theme 4: Project 1 - Optimising assessment of health impacts of air pollution

Aims: Estimate the health burden of total air pollution, and health impacts of feasible reductions in air pollution, selected in consultation with stakeholders in London, and more widely, using WHO and COMEAP recommendations, DH-funded meta-analyses on effects of short-term exposure and on long-... Read more...

Theme 4: Project 2 - Neurocognitive and behavioural impacts of traffic derived pollutants in children

Aims: To test the hypothesis that exposure to traffic derived pollutants, especially those from diesel vehicles, is associated with impaired neurocognitive and behavioural development, employing secondary-school aged children living within the Greater London area.  This will make use of the... Read more...

Theme 4: Project 3 - Nanoparticle exposure assessment

The public health risks associated with exposure to many engineered nanoparticles remain uncertain. Recent studies illustrating similarities between the pulmonary effects of some carbon nanotubes and asbestos, and the well-documented effects of fine particulate air pollution on cardiorespiratory... Read more...

Theme 4: Project 4 - Health Impacts; nanoparticles

The public health risks associated with exposure to many engineered nanoparticles remain uncertain. Recent studies illustrating similarities between the pulmonary effects of some carbon nanotubes and asbestos, and the well-documented effects of fine particulate air pollution on cardiorespiratory... Read more...

Theme 4: Project 5 - Improved in vitro systems for evaluation and comparing toxicity of air pollutants

To build on established networks within the current HPRU, capitalising on the novel systems developed in the toxicological assessment of nanomaterials and other in vitro cell systems in the HPRU, we aim to investigate the mechanistic basis of the adverse health effects of combustion derived... Read more...

Theme 4: Project 7 - Methods for assessing the public health benefits of local transport interventions

Transport interventions have an important role in reducing air pollution concentrations.  Transport interventions within cities are also important for the Environmental Change HPRU, Theme 2 on healthy, sustainable cities.  This joint project plans to take advantage of synergies between the two... Read more...

Theme 4: Project 8 – Association between primary mental health outcomes with air pollution in urban populations

The Clinical Record Interactive Search (CRIS) system has been developed for use by the NIHR Maudsley Biomedical Research Centre and Dementia Biomedical Research Unit at the South London and Maudsley (SLaM) NHS Foundation Trust. CRIS provides authorised researchers with regulated access to a... Read more...