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Theme 2: Project 3 - Environmental and Human Microbiome

Exposure to environmental microbiomes occurs though bioaerosols. This project focusses particularly on the application of molecular methods to the analysis of fungal species in molecular epidemiology.  It links both with Theme I and also to the bioaerosol work in the Environmental Change and Health HPRU. This work will be carried out with members of theme 1 with the purpose of better associating specific fungal exposure with health outcomes. A method for assessment of the speciation of fungal spores in samples will be developed first at the qualitative level with further development to be quantitative. This is difficult because fungal spores vary in size, have segmental duplications over the genome region of interest for speciation and diversity of cell number. There is a lack of understanding of the effects of fungal species on health. Fungal species also form part of the human microbiome and the significance of environmental effects on both the environmental and human microbiome and link to health will form part of the work of this project.

Aim: to better characterise the Environmental and human microbiomes and relationship to health. 

Lead researchers

Dr Emma Marczylo

Investigator

Public Health England

Dr Anna Hansell

Theme 1 Leader: Epidemiological assessment of low level environmental exposures

Imperial College London