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Dr Emma Marczylo



Theme 2 - Modes of toxicity (Biochemical pathways from toxin to disease)

Public Health England

Emma is a Senior Toxicologist within the Toxicology Department at the Centre for Radiation, Chemical and Environmental Hazards, Public Health England, UK. She completed her undergraduate (Biochemistry) degree at Lancaster University in 1996 and her PhD into the production of protoporphyrin IX from aminolaevulinic acid and its derivatives within the Photodynamic Therapy Group of Prof Stan Brown at the University of Leeds in 2003. Whilst finalising her PhD, Emma began a short 6 month contract testing novel antimicrobials within the spin-off company from the Leeds Photodynamic Therapy Group, Photopharmica. In 2004, she moved to the Leicester School of Pharmacy in DeMontfort University, Leicester for her first postdoctoral research position, joining the Cell Signalling Laboratory of Prof Mike Boarder to investigate potential dimerisation of the G protein coupled purinergic receptors. In 2006, Emma moved to the MRC Toxicology Unit for her second postdoctoral research position, joining the Systems Toxicology Group of Prof Tim Gant as a Career Development Fellow to investigate the role of microRNAs in toxicology and becoming a permanent Investigator Scientist in 2008. During the same year, Emma won the CEFIC-LRI Innovative Toxicology Award, a personal award of €100,000 to fund research into male epigenetic transgenerational chemical toxicity using in vivo and in vitro stem cell based systems. In 2012, Emma joined the Centre of Radiation, Chemical and Environmental Hazards at Public Health England to further focus her experience in biochemistry, cellular and molecular biology, toxicology, genomics and bioinformatics on research into the epigenetic mechanisms of multigenerational toxicity, again under the guidance of Prof Tim Gant. Her scientific interests centre on toxicogenomics, particularly next generation sequencing and multigenerational toxicity transmitted through the male germline.

Throughout her career Emma has taught at both the undergraduate and postgraduate level. This has involved laboratory demonstrations, tutorials, lectures and research project supervision. Emma currently has 15+ peer-reviewed publications.